Research
Explore the research, studies, and clinical trials behind the science supporting our products.
| Date | Title | Source |
|---|---|---|
| Mar 2023 | The Tissue Response to Hypoxia: How Therapeutic Carbon Dioxide Moves the Response toward Homeostasis and Away from Instability | International Journal of Molecular Sciences |
| Sep 2011 | A Novel System for Transcutaneous Application of Carbon Dioxide Causing an “Artificial Bohr Effect” in the Human Body | PLOS One |
| Aug 2009 | Clinical and microcirculatory effects of transcutaneous CO2 therapy in intermittent claudication. Randomized double-blind clinical trial with a parallel design | National Library of Medicine |
| Mar 2011 | The effect of transcutaneous application of carbon dioxide (CO₂) on skeletal muscle | National Library of Medicine |
| Jul 2022 | Exploratory clinical trial to evaluate the efficacy and safety of carbon dioxide paste in healthy people | National Library of Medicine |
| Apr 2023 | Local application of a transcutaneous carbon dioxide paste prevents excessive scarring and promotes muscle regeneration in a bupivacaine-induced rat model of muscle injury | National Library of Medicine |
| Nov 2021 | Local Application of Transcutaneous Carbon Dioxide Paste Decreases Inflammation and Accelerates Wound Healing | National Library of Medicine |
| Jan 2019 | Facial application of high-concentration carbon dioxide prevents epidermal impairment associated with environmental changes | National Library of Medicine |
| Nov 2019 | Topical cutaneous application of carbon dioxide via a hydrogel for improved fracture repair: results of phase I clinical safety trial | National Library of Medicine |
| Feb 2021 | The Effect of Dry Carbon Dioxide Bathing on Peripheral Blood Circulation Measured by Thermal Imaging among Patients with Risk Factors of PAD | National Library of Medicine |
| Dec 2020 | The effect of transcutaneous application of gaseous CO2 on diabetic chronic wound healing-A double-blind randomized clinical trial | National Library of Medicine |
| Dec 2014 | Topical cutaneous CO2 application by means of a novel hydrogel accelerates fracture repair in rats | National Library of Medicine |
| Nov 2018 | Transcutaneous Carbon Dioxide Treatment Is Capable of Reducing Peripheral Vascular Resistance in Hypertensive Patients | In Vivo |
| Feb 2026 | Transcutaneous Carbon Dioxide Therapy Significantly Accelerates Diabetic Foot Ulcer Healing: A Multicentre Randomised Controlled Trial | MDPI |